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Abstract The most abundant interstellar molecule, molecular hydrogen (H₂), is practically invisible in cold molecular clouds. Astronomers typically use carbon monoxide (CO) to trace the bulk distribution and mass of H₂in our galaxy and many others. CO observations alone fail to trace a significant component of molecular gas known as “CO-dark” molecular gas, which can be probed with molecules such as OH and CH. We present an extremely sensitive pilot search for the 18 cm hydroxyl (OH) lines in the Andromeda galaxy (M31) with the 100 m Robert C. Byrd Green Bank Telescope. We successfully detected the 1665 and 1667 MHz OH lines in faint emission. The 1665/1667 MHz line ratio displays the characteristic 5:9 ratio predicted under conditions of local thermodynamic equilibrium. To our knowledge, this is the first detection of nonmaser 18 cm OH emission in another galaxy. We compare our OH and Hiobservations with archival CO (1–0) observations. Our OH detection position overlaps with the previously discovered Arp Outer Arm in CO. Our best estimates show that the amount of H₂traced by OH is 100%–140% higher than the amount traced by CO in this sight line. The amount of dark molecular gas implied by dust data supports this conclusion. We conclude that the 18 cm OH lines hold promise as a valuable tool for mapping of the “CO-dark” and “CO-faint” molecular gas phase in nearby galaxies, especially with upcoming multibeam, phased-array feed receivers on radio telescopes, which will allow for drastically improved mapping speeds of faint signals. 

Abstract We present the Local GroupL-Band Survey, a Karl G. Jansky Very Large Array (VLA) survey producing the highest-quality 21 cm and 1–2 GHz radio continuum images to date, for the six VLA-accessible, star-forming, Local Group galaxies. Leveraging the VLA’s spectral multiplexing power, we simultaneously survey the 21 cm line at high 0.4 km s⁻¹velocity resolution, the 1–2 GHz polarized continuum, and four OH lines. For the massive spiral M31, the dwarf spiral M33, and the dwarf irregular galaxies NGC 6822, IC 10, IC 1613, and the Wolf–Lundmark–Melotte Galaxy, we use all four VLA configurations and the Green Bank Telescope to reach angular resolutions of <5″ (10–20 pc) for the 21 cm line with <10²⁰cm⁻²column density sensitivity, and even sharper views (<2″; 5–10 pc) of the continuum. Targeting these nearby galaxies (D ≲ 1 Mpc) reveals a sharp, resolved view of the atomic gas, including 21 cm absorption, and continuum emission from supernova remnants and Hiiregions. These data sets can be used to test theories of the abundance and formation of cold clouds, the driving and dissipation of interstellar turbulence, and the impact of feedback from massive stars and supernovae. Here, we describe the survey design and execution, scientific motivation, data processing, and quality assurance. We provide a first look at and publicly release the wide-field 21 cm Hidata products for M31, M33, and four dwarf irregular targets in the survey, which represent some of the highest-physical-resolution 21 cm observations of any external galaxies beyond the LMC and SMC. 

Measuring the properties of the cold neutral medium (CNM) in low-metallicity galaxies provides insight into heating and cooling mechanisms in early Universe-like environments. We report detections of two localized atomic neutral hydrogen (Hi) absorption features in NGC 6822, a low-metallicity (0.2 Z⊙) dwarf galaxy in the Local Group. These are the first unambiguous CNM detections in a low-metallicity dwarf galaxy outside the Magellanic Clouds. The Local Group L-Band Survey (LGLBS) enabled these detections due to its high spatial (15 pc for Hi emission) and spectral (0.4 km s−1) resolution. We introduce LGLBS and describe a custom pipeline to search for Hi absorption at high angular resolution and extract associated Hi emission. A detailed Gaussian decomposition and radiative transfer analysis of the NGC 6822 detections reveals five CNM components, with key properties: a mean spin temperature of 32±6 K, a mean CNM column density of 3.1×1020 cm−2, and CNM mass fractions of 0.33 and 0.12 for the two sightlines. Stacking non-detections does not reveal low-level signals below our median optical depth sensitivity of 0.05. One detection intercepts a star-forming region, with the Hi absorption profile encompassing the CO (2−1) emission, indicating coincident molecular gas and a depression in high-resolution Hi emission. We also analyze a nearby sightline with deep, narrow Hi self-absorption dips, where the background warm neutral medium is attenuated by intervening CNM. The association of CNM, CO, and Hα emissions suggests a close link between the colder, denser Hi phase and star formation in NGC 6822. 

Transfusion of red blood cells (RBCs) is one of the most valuable and widespread treatments in modern medicine. Lifesaving RBC transfusions are facilitated by the cold storage of RBC units in blood banks worldwide. Currently, RBC storage and subsequent transfusion practices are performed using simplistic workflows. More specifically, most blood banks follow the “first-in-first-out” principle to avoid wastage, whereas most healthcare providers prefer the “last-in-first-out” approach simply favoring chronologically younger RBCs. Neither approach addresses recent advances through -omics showing that stored RBC quality is highly variable depending on donor-, time-, and processing-specific factors. Thus, it is time to rethink our workflows in transfusion medicine taking advantage of novel technologies to perform RBC quality assessment. We imagine a future where lab-on-a-chip technologies utilize novel predictive markers of RBC quality identified by -omics and machine learning to usher in a new era of safer and precise transfusion medicine.